STUDIES IN VITAMIN E DEFICIENCY

Studies of Vitamin Deficiency.

Vitamin E Deficiency in the Monkey . Iv .

NEMIA regularly develops in the rhesus monkey (Macaca mulatta) when it is deprived of vitamin E.1 The anemia is accompanied by granulocytosis,’ an increased concentration of bone marrow deoxyribonucleic acid,2 a reduction in the maximal Cr5’ survival time of the erythrocytes,3 a slightly elevated reticulocyte count1 and a prompt reticulocytosis following vitamin E administration. This combinati...

Vitamin E Deficiency in the Monkey

Eight young rhesus monkeys were fed a purified diet devoid of vitamin E. After from 6 to 13 months of feeding, all the animals developed signs of vitamin E deficiency. The signs of vitamin E deficiency in the monkey include muscular dystrophy, elevated excretion of creatine, allantoin, and free amino acids and decreased excretion of creatinine. The vitamin E-deficient monkeys all developed anem...

Ataxia with Vitamin E Deficiency in Norway

OBJECTIVE Ataxia with vitamin E deficiency (AVED) is a rare autosomal recessive neurological disorder which usually starts in childhood. The clinical presentation is very similar to Friedreich ataxia, most patients have progressive truncal and extremity ataxia, areflexia, positive Babinski sign, dysarthria and sensory neuropathy. METHODS We made an inquiry to our colleagues in Norway, we incl...

Isolated vitamin E deficiency and progressive ataxia.

A case of progressive spinocerebellar syndrome due to isolated vitamin E deficiency is reported. Measurement of the vitamin E concentration in serum should be included when investigating all children with unexplained, progressive ataxia, even in the absence of malabsorption. Replacement treatment in patients with a vitamin E deficiency can arrest or improve the associated neurological disorder.